| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3932689 | Fertility and Sterility | 2011 | 4 Pages |
Abstract
Expression of claudin-11, which builds up blood–testis barrier (BTB), was increased in decreased spermatogenesis, including in hypospermatogenesis, spermatocytic and maturation arrest, and Sertoli cell only (SCO) testes. Increased claudin-11 immunoreactivity was observed at the inter-Sertoli tight junctions in maturation arrest and in the cytoplasm of Sertoli cells in SCO. The late spermatogenic wave may negatively regulate claudin-11 gene activation and the subcellular localization of claudin-11 in Sertoli cells, thus altering the BTB in the human testis.
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Authors
Won Heum Nah, Jae Eun Lee, Hyun Jun Park, Nam Cheol Park, Myung Chan Gye,