Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3932894 | Fertility and Sterility | 2010 | 4 Pages |
Abstract
In this open-label, randomized, multiple-dose, two-treatment crossover study, 24 postmenopausal women with moderate to severe atrophic vaginitis received 0.3 mg conjugated estrogens daily for 14 days: 7 days orally (0.3 mg tablet) and 7 days vaginally (0.5 g cream). Steady-state plasma concentrations of E2 and estrone were one-third lower after vaginal versus oral administration of conjugated estrogens.
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Authors
Mary Beth Dorr, Anita L. Nelson, Philip R. Mayer, Radhika P. Ranganath, Paul M. Norris, Eileen C. Helzner, Richard A. Preston,