| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3933563 | Fertility and Sterility | 2010 | 4 Pages |
Abstract
The present study investigates the expression of the coactivator Bridge-1 in the human ovary and its role in activin A signaling in the human granulosa cell line HGL-5. Expression of Bridge-1 can be stimulated by activin A, an important factor for follicle maturation, matching the increase of Smad 2, 3, and 4; treatment with Bridge-1–small interfering RNA is decreasing not only the expression of Bridge-1 but also the expression of Smad2, 3, and 4 in HGL-5 cells.
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Authors
Constanze Banz, Birte Münchow, Klaus Diedrich,