Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3935878 | Fertility and Sterility | 2011 | 9 Pages |
Abstract
Human macrophages, cultured under hypoxic conditions, release factors that induce the expression of the adhesion phenotype in normal peritoneal fibroblasts. Particularly, TGF-β1 reproduces this response by regulating the expression of TGF-β1, VEGF, and type I collagen in a dose-dependent manner. Therefore, these findings highlight an important role for human macrophages in peritoneal wound healing.
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Authors
Jennell C. M.S., Zhong L. M.D., Michael P. M.D., Ghassan M. Ph.D.,