Article ID Journal Published Year Pages File Type
3936337 Fertility and Sterility 2010 8 Pages PDF
Abstract

ObjectiveTo compare the semen quality and age-specific changes in men between the 1980s and 2000s.DesignProspective study.SettingAndrology laboratory, University of Calcutta, India.Patient(s)A semen sample was obtained from 3729 men presenting for infertility problems in two distinct decades, that is, between 1981–85 and 2000–2006.Intervention(s)Subjects with sperm count >20 × 106/mL without any extreme pathological disorders were selected. Samples having a major liquefaction problem were excluded.Main Outcome Measure(s)A standard World Health Organization procedure for semen analysis was performed that included assessment of volume, sperm concentration, and percentage motility. The motility parameters were further classified into forward progressive motility and nonprogressive motility.Result(s)The present large-scale study confirms a significant decline in the sperm motility parameters and seminal volume in the present decade. However, no change in overall sperm concentration was noted. A decline was seen in sperm motility with increasing age in both decades.Conclusion(s)There are significant changes in sperm motility and volume between the two decades, and the age-related changes in semen parameters are also different in the two decades.

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