Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3936449 | Fertility and Sterility | 2009 | 4 Pages |
Abstract
Eighteen normal women underwent pituitary down-regulation with leuprolide, followed by a 10-day treatment with 0.2 mg/d transdermal estradiol (E2) with subsequent allocation to one of two 10-day estradiol regimens plus 40 mg daily intramuscular P: supraphysiologic (0.2 mg/d transdermal E2 mg/d vaginal micronized E2) or subphysiologic (no exogenous E2 treatment). Average E2 and P in the supraphysiologic, physiologic, and subphysiologic groups were 1,175.9 pg/mL and 17.5 ng/mL, 136.9 pg/mL and 21.2 pg/mL, and 23.8 ng/mL and 22.0 ng/mL, respectively, and there were no differences between groups in endometrial histology or expression of biomarkers of receptivity.
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Authors
Jeremy M. Groll, Rebecca S. Usadi, Bruce A. Lessey, Ruth Lininger, Steven L. Young, Marc A. Fritz,