Cervical mucus removal before embryo transfer in women undergoing in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis of randomized controlled trials

A meta-analysis from the available moderate to low quality trials provides very little evidence of an overall benefit of cervical mucus removal before embryo transfer for women undergoing IVF/ICSI. Due to problems of clinical diversity, statistical heterogeneity, and risk of bias, additional pragmatic multicenter RCTs are needed to evaluate the possible small benefit of cervical mucus removal before embryo transfer.