Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3936525 | Fertility and Sterility | 2014 | 10 Pages |
Abstract
Three WNT/-catenin pathway inhibitors specifically block human leiomyoma growth and proliferation, suggesting that the canonical WNT pathway may be a potential therapeutic target for the treatment of uterine leiomyoma. Our findings provide rationale for further preclinical and clinical evaluation of ICAT, niclosamide, and XAV939 as candidate antitumor agents for uterine leiomyoma.
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Authors
Masanori M.D., Ph.D., Ping Ph.D., Antonia M.Sc., Molly B. M.D., John S. M.Sc., Stacy A. B.Sc., Cara J. Ph.D., Serdar E. M.D.,