Article ID Journal Published Year Pages File Type
3936955 Fertility and Sterility 2009 6 Pages PDF
Abstract

ObjectiveTo study the effect of freeze–thaw on embryos derived from intracytoplasmic sperm injection (ICSI) using surgically retrieved and ejaculated spermatozoa.DesignRetrospective study.SettingPrivate IVF center.Patient(s)Three hundred eighty-three patients undergoing frozen–thawed ET cycles.Intervention(s)Testicular sperm aspiration (TESA) or percutaneous epididymal sperm aspiration (PESA) were the sperm surgical retrieval methods used for ICSI. Embryos resulting from ICSI using surgically retrieved and ejaculated spermatozoa were frozen, thawed, and transferred.Main Outcome Measure(s)Post-thaw survival, implantation, and pregnancy rates.Result(s)No differences were found between the ejaculated sperm and TESA/PESA groups in terms of post-thaw survival rate (68.4% vs. 66.1%, respectively), pregnancy rate (20.1% vs. 16.1%), and implantation rate (10.6% vs. 12.7%). Similar results were found for those variables when comparing TESA and PESA groups.Conclusion(s)Cleavage embryos arising from ICSI cycles using testicular and epididymal spermatozoa can be frozen with survival, pregnancy, and implantation rates comparable to those obtained with ejaculated spermatozoa.

Related Topics
Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
Authors
, , , , , , ,