Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3937145 | Fertility and Sterility | 2012 | 9 Pages |
Abstract
Treatment with S1P can inhibit the apoptosis of granulosa cells in response to oxidative stress induced by H2O2. The protective effect of S1P is mediated by activating the PI3K/Akt pathway, and the antiapoptotic effect of S1P is mainly mediated through the S1P1 and S1P3 receptor.
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Authors
Tatsuo M.D., Akira M.D., Ph.D., Tomoko M.D., Mika M.D., Bayasula M.D., Hiroharu M.D., Sachiko M.D., Shuichi M.D., Maki M.D., Tomomi M.D., Fumitaka M.D.,