| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3940774 | Fertility and Sterility | 2006 | 6 Pages |
Abstract
Mevastatin inhibits proliferation of theca-interstitial cells by a mechanism that involves depletion of mevalonic acid and selective inhibition of basal and insulin-induced activity of Erk1/2 pathway, but not Akt/PKB pathway. These effects of mevastatin may be a result of decreased isoprenylation of small GTPases.
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Authors
Jakub Ph.D., Nastaran M.D., Piotr M.D., Ph.D., Izabela M.Sc., Antoni J. M.D.,