Article ID Journal Published Year Pages File Type
3941016 Fertility and Sterility 2006 5 Pages PDF
Abstract

By means of a videomicroscopy system and a computer image analysis, we performed chemotaxis assays to detect true chemotaxis in human spermatozoa, in parallel to immunohistochemistry detection of progesterone inside the cumulus cells. Progesterone indeed chemotactically guides mammalian spermatozoa at very low hormone concentrations, and the cumulus oophorus could be a potential place for sperm chemotaxis mediated by progesterone in vivo.

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Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
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