| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3941296 | Fertility and Sterility | 2009 | 4 Pages |
Abstract
Human embryonic stem cells have the greatest potential for regenerative and reproductive medicine; unfortunately, their full application is limited by ethical and technical problems. In order to overcome these problems and get patient specific pluripotent cells from somatic cells, the field of reprogramming has moved to the generation of induced pluripotent stem cells by overexpression of four transcription factors after viral infection of the patient's somatic cells. In the present paper we review the limitations and milestones of this technique in both regenerative and reproductive medicine.
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Authors
Roberto Ensenat-Waser, Antonio Pellicer, Carlos Simon,