| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3941425 | Fertility and Sterility | 2009 | 4 Pages |
Because ovarian follicular growth occurs in three dimensions, and because follicular maturation (increased E2) is a result of an increase in the three-dimensional follicular surface area where testosterone (E2 precursor)–producing theca interna cells are located, the three-dimensional follicular volume and the three-dimensional follicular surface area describe the three-dimensional follicular growth and maturation, respectively, more accurately than does the two-dimensional follicular diameter alone. Therefore, we present a mathematical model that describes the relationship of the two-dimensional follicular diameter, the three-dimensional follicular volume, and the three-dimensional follicular surface area to the three-dimensional follicular growth and maturation.
