Article ID Journal Published Year Pages File Type
3941473 Fertility and Sterility 2009 4 Pages PDF
Abstract

The blastomere biopsy procedure does not affect preimplantation embryo development or global patterns of gene expression in a mouse model of Preimplantation Genetic Testing (PGT). However, zona breaching, which is inherent to the blastomere biopsy procedure, causes significant premature and sometimes abnormal hatching.

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The effect of blastomere biopsy on preimplantation mouse embryo development and global gene expression
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