| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3941505 | Fertility and Sterility | 2009 | 4 Pages |
Abstract
This was a preliminary study to determine the effect of aromatase inhibitors in preventing the flare induced by GnRH agonist (GnRH-a) in women with endometriosis (n = 9) or leiomyomata (n = 4) who were given letrozole on the first 5 days of the GnRH-a therapy. Serum LH and FSH levels showed the typical flare 1 day after the injection of the GnRH-a; however, E2 declined immediately after letrozole administration and was notably suppressed at 1, 2, and 4 days after GnRH-a. No patients complained of clinical symptoms typical of the GnRH-a flare phenomenon.
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Authors
Mohamed A. Bedaiwy, Noha A. Mousa, Robert F. Casper,