Article ID Journal Published Year Pages File Type
3941610 Fertility and Sterility 2008 10 Pages PDF
Abstract

ObjectiveTo compare success rates in black and white women undergoing IVF.DesignRetrospective cohort study.SettingSociety for Assisted Reproductive Technology member clinics in 1999–2000 that performed ≥50 cycles of IVF and reported race/ethnicity in >95% of cycles.Patient(s)Women receiving 80,309 IVF cycles.Intervention(s)IVF using nondonor embryos.Main Outcome Measure(s)Live-birth rate per cycle started.Result(s)Black, white, and other race/ethnicity women underwent 3666 (4.6%), 68,607 (83.5%), and 8036 (11.9%) IVF cycles, respectively. Spontaneous abortions were more common among black women. The live-birth rate was 26.3% (95% confidence interval [CI], 25.9%–26.7%) among white women compared with 18.7% (95% CI, 17.5%–20.1%) among black women (rate ratio, 1.41). After controlling for increased tubal and uterine factor infertility among blacks and other characteristics, black race was an independent risk factor for not achieving a live birth (adjusted relative risk, 1.21; 95% CI, 1.12–1.36 if no prior ART, and RR, 1.38; 95% CI, 1.20–1.57 if prior ART). For cryopreserved embryo cycles, live-birth rates were equivalent.Conclusion(s)Black women, who represented 7.8% of married reproductive-age women in the United States at that time, were underrepresented among IVF recipients. Race is a marker for prognosis that is not explained by characteristics available in the registry data set.

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