Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3943565 | Gynecologic Oncology | 2013 | 10 Pages |
Abstract
⺠K-1 inhibits endometrial cancer cellular growth and tumor xenograft growth via interfering with GPR30/EGFR/ERK1/2 activation. ⺠Compound showed dual targeting i.e. non-genomic GPR30 signaling and genomic ER signaling in endometrial cancer cells. ⺠Benzopyran derivative K-1 could serve as a candidate molecule for future development as a chemotherapeutic agent against human endometrial cancer.
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Authors
V. Chandra, I. Fatima, R. Saxena, M.K. Hussain, K. Hajela, P. Sankhwar, B.G. Roy, S. Chandna, A. Dwivedi,