Article ID Journal Published Year Pages File Type
3951764 International Journal of Gynecology & Obstetrics 2015 4 Pages PDF
Abstract

ObjectiveTo examine placental vascularization using three-dimensional power Doppler (3DPD) ultrasonography in pregnancies complicated by intrauterine growth restriction (IUGR).MethodsThe present prospective study was conducted at the University of Szeged (Szeged, Hungary) from February 2012 to March 2013. Women with a singleton pregnancy who attended the maternity outpatient ward in the second or third trimester were enrolled consecutively. Women were divided into two groups: those with a normal pregnancy and those with a pregnancy complicated by IUGR. Three 3DPD indices—vascularization index (VI), flow index (FI), and vascularization flow index (VFI)—were assessed.ResultsA total of 223 women were enrolled: 171 were in the control group and 52 in the IUGR group. Median VI was 3.7% (interquartile range [IQR] 3.2%–4.2%) in the IUGR group and 10.1% (IQR 8.6%–10.9%) in the control group (P = 0.001). Median FI was 40.0 (IQR 39.7–42.5) in the IUGR group and 45.1 (IQR 44.1–53.1) in the control group (P = 0.012). Median VFI was 2.2 (IQR 2.1–2.4) in the IUGR group and 4.8 (IQR 4.4–5.3) in the control group (P < 0.001).ConclusionPlacental vascularization was reduced in pregnancies complicated by IUGR.

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