| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3965630 | Journal of Reproduction and Contraception | 2010 | 6 Pages |
Abstract
ObjectiveTo evaluate the spermicidal activity of Passiflora edulis extract on human spermatozoa.MethodsHuman spermatozoa were incubated with P. edulis extracts and their motility and viability were evaluated; additionally, the cytotoxic effect of the extracts was evaluated by the tetrazolium bromide (MTT) reduction assay.ResultsThe motility and viability were decreased immediately after treatment with a 21% dilution of the supernatant of the extract of P. edulis (P<0.001). No cytotoxic effect of the extracts studied was found on proliferation of MDBK and VERO cells.ConclusionThese results may open the way for the use of P. edulis as a spermicidal product with less adverse effects.
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