Embryos refrozen–thawed by vitrification lead to live births: Case report

ObjectiveTo describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos.DesignCase report.SettingPrivate fertility clinic.SubjectsTwo infertility couple.InterventionsRefrozen blastocysts by vitrification derived from supernumerary embryos.Main outcome measuresObstetric and pediatric results.ResultsTwo pregnancies obtained from refrozen–warmed blastocysts led to two healthy babies being born without clinical or genetic problems.ConclusionThese case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular.