Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3967407 | Obstetrics, Gynaecology & Reproductive Medicine | 2007 | 7 Pages |
Women with kidney disease who become pregnant are at risk of further damage to their kidneys and an adverse pregnancy outcome. In general, women with mild renal dysfunction (Scr<125 μmol/litre) usually pass through pregnancy without adverse impact on their kidneys, although complications such as pre-eclampsia, fetal growth restriction and pre-term delivery are more likely. Women with severe renal impairment (Scr >220 mmol/litre) have a 1:3 risk of an accelerated decline in renal function because of pregnancy and pre-eclampsia, fetal growth restriction and pre-term delivery become common place. Clinical features such as pre-existing hypertension, proteinuria >1 g/24 hour and/or urinary tract infections add to the likelihood of complications. This article discusses important issues for women with kidney disease in pregnancy.