Tumor de células de Sertoli-Leydig ovárico

We present the rare case of a 62-year-old woman who developed an ovarian tumor associated with severe hirsutism, hypertension, renal insufficiency, and hyperparathyroidism. Hormone evaluation showed high plasma testosterone and estradiol values, with suppressed gonadotropins. Ultrasound examination and computed tomography revealed a large pelvic tumor. Differential diagnosis with a Sertoli-like endometrioid carcinoma of the ovary was contemplated, but inhibin-positive expression established the diagnosis of Sertoli-Leydig cell tumor. Postsurgical outcome was favorable, with normal plasma values of sexual steroids and an increase of gonadotropins to within the normal postmenopausal range.