Sequential embryo scoring as a predictor of aneuploidy in poor-prognosis patients

Preimplantation genetic diagnosis for aneuploidy screening (PGS) is a technology used to determine the chromosome complement of an embryo prior to its transfer into the uterus. Despite promising initial results, PGS has not drastically increased delivery rates. This study compares the delivery rates of patients having PGS and those canceling the plan for PGS opting for an embryo transfer without it. Embryos were selected by the PGS result (normal or abnormal) for PGS patients or based on embryo morphology for those patients who did not undergo PGS. The results of this study showed that there was no difference in delivery rates between these two groups of patients and, in fact, a lower delivery rate after PGS in patients having less than six embryos.