| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3971532 | Reproductive BioMedicine Online | 2010 | 4 Pages |
Abstract
Magnetic activated cell sorting (MACS) with annexin V microbeads recognizes externalized phosphatidylserine (PS) residues on the surface of apoptotic spermatozoa. The successful use of this novel technique applied to a highly apoptotic semen sample before performing intracytoplasmic sperm injection (ICSI) is reported here. The use of annexin V microbeads for selecting non-apoptotic spermatozoa seems to reduce the percentage of altered cells, improving the chance of pregnancy after ICSI.
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Authors
Vanesa Y. Rawe, Heydy Uriondo Boudri, Cristian Alvarez Sedó, Martina Carro, Sergio Papier, Florencia Nodar,