Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3974288 | Seminars in Fetal and Neonatal Medicine | 2010 | 6 Pages |
Abstract
SummaryTwin pregnancy is associated with a high risk of congenital malformations. This review covers the risk of such anomalies in both dizygotic and monozygotic twin pregnancies, and discusses current insights into the associations relating to zygosity, chorionicity and genetic factors. The pathological basis of specific malformations unique to the monochorionic twinning process, including conjoined twinning and twin reversed arterial perfusion (TRAP) sequence, is discussed in more detail, and factors contributing to the higher perinatal mortality rate in multiple pregnancies are addressed.
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Authors
Martin A. Weber, Neil J. Sebire,