Article ID Journal Published Year Pages File Type
3974288 Seminars in Fetal and Neonatal Medicine 2010 6 Pages PDF
Abstract

SummaryTwin pregnancy is associated with a high risk of congenital malformations. This review covers the risk of such anomalies in both dizygotic and monozygotic twin pregnancies, and discusses current insights into the associations relating to zygosity, chorionicity and genetic factors. The pathological basis of specific malformations unique to the monochorionic twinning process, including conjoined twinning and twin reversed arterial perfusion (TRAP) sequence, is discussed in more detail, and factors contributing to the higher perinatal mortality rate in multiple pregnancies are addressed.

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Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
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