Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3974361 | Seminars in Fetal and Neonatal Medicine | 2008 | 7 Pages |
Abstract
SummaryPrenatal fetal sex determination is undertaken in women at high risk of serious genetic disorders affecting a specific sex. Traditionally, this is undertaken by invasive testing, usually chorionic villus sampling, which carries a risk of miscarriage of around 1%. The identification of cell-free fetal DNA in the maternal circulation has allowed the development of ‘non-invasive prenatal diagnostic tests’, which permit fetal sex determination without risk to the pregnancy.
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Authors
Kirstin M. Finning, Lyn S. Chitty,