Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3975818 | Taiwanese Journal of Obstetrics and Gynecology | 2009 | 6 Pages |
Abstract
SummaryWomen who are carrying a trisomy 13 fetus are prone to have an abnormal placenta as well as to develop preeclampsia in the second and third trimesters. This article provides a comprehensive review of placental abnormalities, such as small placental volume, reduced placental vascularization, a partial molar appearance of the placenta and placental mesenchymal dysplasia, and preeclampsia associated with trisomy 13 pregnancies. The candidate preeclampsia-causing genes on chromosome 13, such as sFlt1, COL4A2 and periostin, are discussed.
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health