Article ID Journal Published Year Pages File Type
3975940 Taiwanese Journal of Obstetrics and Gynecology 2008 8 Pages PDF
Abstract

SummaryPrenatal screening with α-fetoprotein (AFP) and ultrasonography have allowed the prenatal diagnosis of neural tube defects (NTDs) in current obstetric care, and open spina bifida has been considered a potential candidate for in utero treatment in modern pediatric surgery. This article provides an overview of maternal serum AFP screening, amniotic fluid AFP assays, amniotic fluid acetylcholinesterase immunoassays and level II ultrasound for NTDs, prenatal repair of fetal myelomeningocele, recurrence risk of NTDs, and differential diagnosis of NTDs on prenatal ultrasound.

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Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health