Do changes in interfraction organ at risk volume and cylinder insertion geometry impact delivered dose in high-dose-rate vaginal cuff brachytherapy?

A more posterior y angle of insertion was found to increase rectal D2cc leading us to believe that angling the vaginal cylinder anteriorly may reduce rectal dose without significantly increasing bladder dose. Although attention should be paid to OAR volume and CIG to minimize OAR dose, the clinical significance of P − F changes remains yet to be shown.