Dosimetric outcomes in prostate brachytherapy: Is downsizing the prostate with androgen deprivation necessary?

In the present study, patients with prostate volumes >50 cc have postimplant dosimetry parameters similar to patients with prostate volumes ≤50 cc for D90, V100, and V150; and significantly lower values for V200. These results suggest that patients with large prostate volumes may not need to be routinely placed on hormonal therapy; sparing patients the side effects of hormonal therapy, and sparing the health care system the costs of luteinizing hormone-releasing hormone agonist injections.