Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3978591 | Bulletin du Cancer | 2013 | 6 Pages |
Abstract
Numerous studies have demonstrated that a significant change in weight during chemotherapy treatment was a factor of poor prognosis in early breast cancer women. However, the causes and mechanisms involved in this phenomenon are not fully known. This review summarizes current knowledge about the causes of energy imbalance during chemotherapy treatment and the mechanisms that have been proposed as responsible for the increased risk of relapse and death in this population. Current preventive strategies focus on physical activity programs but also on the use of metformin during and after chemotherapy.
Keywords
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Authors
Ãmilie Gadéa, Ãmilie Thivat, Qian Wang-Lopez, Marie Viala, Rodolphe Paulon, Ãloïse Planchat, Jean-Baptiste Chadeyras, Charles Merlin, Bruno Coudert, Yves-Jean Bignon, Béatrice Morio, Xavier Durando,