Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3979688 | Cancer Treatment Communications | 2013 | 5 Pages |
Abstract
We present the case of a 27 year old woman with widely disseminated metastatic adenocarcinoma of the lung who outlived stage IV diagnosis of NSCLC by more than 4 years. Based on rebiopsy and molecular diagnostics of oncogene dependency, appropriately targeted therapies were successfully employed up to a fifth line oral monotherapy with the ErbB family blocker afatinib for a final 11 months. We stress the importance of rebiopsies, the corresponding selection of targeted therapies, and the observed gain in quality of live even in end stage disease.
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Authors
Jan Stoehlmacher-Williams, Gerhard Ehninger, Dieter R. Zimmermann, Sabine Merkelbach-Bruse, Hans-Ulrich Schildhaus, Reinhard Buettner,