| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3981365 | Clinical Radiology | 2015 | 6 Pages |
•Renal volume correlated moderately with renal function.•RCV correlated no better with renal function than RPV.•Volume of the operated kidneys correlated better with GFR than that of the other side.
AimTo evaluate the correlations between renal cortical volume (RCV), renal parenchymal volume (RPV), and renal function in patients with renal tumours before and after laparoscopic partial nephrectomy (LPN).Materials and methodsThirty-five patients with a single unilateral renal tumour who had undergone contrast-enhanced computed tomography (CT) and renal nuclear scintigraphy before and after LPN were retrospectively studied. RCV and RPV were calculated as renal volume, excluding tumours or cysts, using a semi-automatic segmentation program. The correlations between RCV, RPV, and glomerular filtration rate (GFR) were undertaken preoperatively and postoperatively using the Pearson correlation coefficient.ResultsPreoperatively, the correlations between RCV and GFR, and RPV and GFR for the operated kidneys was r=0.502 (p=0.002) and 0.527 (p=0.001), respectively, whereas the correlations for the contralateral side were r=0.384 (p=0.023) and r=0.412 (p=0.014). The mean RCV and RPV of the operated kidneys decreased by 27.4% and 24.8%. The mean split GFR of the operated kidneys decreased by 36.4%. Postoperatively, residual RCV (r=0.619, p<0.001) and RPV (r=0.593, p<0.001) correlated moderately with the GFR of the operated kidneys.ConclusionsRenal volume, both RCV and RPV, had a moderate relationship with renal function before and after operation. CT-based renal volume measurements could serve as a simple and effective method for estimation of postoperative renal function.
