Article ID Journal Published Year Pages File Type
3981539 Clinical Radiology 2015 5 Pages PDF
Abstract

•We assess the frequency of malignancy in lesions characterized as benign (BI-RADS® 2) on breast MRI.•The frequency of malignancy in breast lesions classified as BI-RADS® 2 is zero.•Breast biopsies are unnecessary in these cases.

AimTo assess the frequency of malignancy in lesions characterized as benign [Breast Imaging—Reporting and Data System (BI-RADS) 2] on breast MRI.Materials and methodsIn this institutional review board-approved retrospective single-centre study, 1265 consecutive patients (mean age 50±13 years), undergoing dynamic contrast-enhanced MRI (1.5 T) of the breast during a 6 year time period, were eligible. This study investigated the MRI characteristics and frequency of malignancy in 192 of these patients with breast lesions classified as BI-RADS 2. Examinations were read during clinical practice and classified according to the MRI BI-RADS lexicon. Based on the patient's and referring physician's preferences, lesions were either histopathologically verified or were subjected to both clinical and imaging follow-up of at least 2 years (range 2–9 years). Descriptive statistical metrics were calculated.ResultsAccording to the standard of reference, 0 of 192 (0%) lesions classified as BI-RADS 2 were malignant. Histopathology was available in 67 (34.9%) lesions and revealed benign findings exclusively. The remaining 125 (65.1%) lesions did not exhibit changes during the follow-up period and were, therefore, considered negative for malignancy.ConclusionsThe frequency of malignancy in breast lesions classified as BI-RADS 2 is zero. As a consequence, breast biopsies are unnecessary in these cases.

Related Topics
Health Sciences Medicine and Dentistry Oncology
Authors
, , , , , ,