Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3981682 | Clinical Radiology | 2012 | 12 Pages |
Abstract
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) is an umbrella acronym for inflammatory clinical conditions whose common denominator is aseptic osteoarticular involvement with characteristic skin lesions. It involves all ages, can involve any skeletal site, and has variable imaging appearances depending on the stage/age of the lesion and imaging method. It mimics important differentials including infection and neoplasia. Awareness of the imaging features, especially in the spine, facilitates early diagnosis, prevents repeated biopsies, and avoids unnecessary surgery, while initiating appropriate treatment.
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Authors
R. Depasquale, N. Kumar, R.K. Lalam, B.J. Tins, P.N.M. Tyrrell, J. Singh, V.N. Cassar-Pullicino,