CT-guided percutaneous core biopsy of deep face and skull-base lesions

AimTo evaluate the diagnostic accuracy of deep face and skull-base computed tomography (CT)-guided core biopsy.Materials and methodsSeventeen patients underwent CT-guided percutaneous core biopsies of deep face and skull-base lesions. One biopsy was repeated due to a non-diagnostic sample so 18 biopsy procedures were evaluated. The 17 lesions were centred within the central skull base (n = 2), parapharyngeal (n = 3), retropharyngeal spaces (n = 4), masticator (n = 3), pterygopalatine fossa (n = 1), and deep lobe of parotid (n = 4). Subzygomatic (n = 7), retromaxillary (n = 9), suprazygomatic (n = 1), and transparotid (n = 1) needle approaches were used. The diagnostic accuracy was either assessed by a positive histological result from the operative specimen or based on treatment response and clinical follow-up.ResultsNo immediate or delayed procedural complications were encountered. A histological diagnosis was obtained in 16 of the 18 biopsies (89% diagnostic yield). The pathological diagnosis was confirmed by surgical excision (5/18 biopsies) and by predicted treatment response or clinical follow-up (10/18 biopsies). Diagnosis could not be confirmed for three of the 18 biopsies. The diagnostic accuracy of core biopsy was 13 of 15 (87%) for all samples.ConclusionCT-guided percutaneous deep face core biopsy is a safe technique with good diagnostic accuracy, allowing diagnosis of benign disease and classification of malignant disease.