| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3988571 | Gaceta Mexicana de Oncología | 2016 | 4 Pages |
ResumenSe presenta el caso de una paciente con anemia (hemoglobina 9 g/dL) de 4 años de evolución. Referida al Servicio de Medicina Interna por presentar desde hace 6 meses fatiga, disnea a medianos esfuerzos y síncope, asociado además a dolor urgente en región costal irradiado a columna dorso lumbar y miembros inferiores. Exámenes sanguíneos revelaron hemoglobina 8.4 g/dL, además de altos niveles de inmunoglobulina A. La electroforesis de proteínas reveló pico monoclonal inmunoglobulina A tipo kappa. La inmunohistoquímica demostró células reactivas a CD138, compatibles con mieloma múltiple. Llamó fuertemente la atención la presencia de osteoesclerosis y pocas células plasmáticas en la biopsia de médula ósea. Realizamos una revisión sobre mieloma múltiple, su presentación clínica y diagnóstico diferencial.
The case is presented of a female patient with history of anaemia (haemoglobin 9 g/dL) of 4 years onset, who was referred to the Internal Medicine department complaining of fatigue, dyspnoea, and syncope. She also had a burning pain in the costal region radiating to dorsal and lumbar spine, and lower limbs, which persisted for more than 6 months. The laboratory results reported a haemoglobin value of 8.4 g / dL. There were also high levels of immunoglobulin A (2087). The serum protein electrophoresis revealed the presence of a monoclonal peak, with immunofixation showing the presence of Kappa type IgA. The histopathological examination of the bone marrow biopsy showed the presence of osteosclerosis and few plasma cells. Multiple myeloma was confirmed by CD 138 immunohistochemical staining. A review is presented on multiple myeloma, its clinical presentation, and differential diagnosis.
