Article ID Journal Published Year Pages File Type
3990335 Journal of Thoracic Oncology 2012 8 Pages PDF
Abstract
The increased sensitivity of PC-9/Met cells to SN-38 compared with that of PC-9 cells was partially because of topo I activities resulting from increased topo I mRNA and protein expression caused by MET signaling.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Oncology
Preview
MET Increases the Sensitivity of Gefitinib-Resistant Cells to SN-38, an Active Metabolite of Irinotecan, by Up-Regulating the Topoisomerase I Activity
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