Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3992052 | Journal of Thoracic Oncology | 2008 | 6 Pages |
Abstract
Deletions of the 3p22.1 and 10q22.3 regions can be reliably detected by FISH. As one progresses from the contralateral normal bronchus to the bronchus on the side of tumor and the tumor itself, the percentage of chromosomal deletions increases in a statistically significant fashion. This suggests that, FISH analysis of bronchoscopic brushes may be useful for identifying patients at high risk for developing non-small cell lung cancer.
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Authors
Sai MB, BS, Ara A. MD, Tanweer MD, Lei MS, Ricardo BS, Nebiyou B. PhD, Wayne L. MD, Feng MD, PhD, Reza J. MD, David C. MD, Margaret R. MD, MPH, Stephen G. MD, Garrett L. MD, Jack A. MD, Ruth L. MD,