Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3992612 | Journal of Thoracic Oncology | 2008 | 4 Pages |
Abstract
Carcinoids are malignant neuroendocrine tumors consisting of a spectrum of neoplasms from low-grade typical carcinoid to high-grade small cell carcinoma. We report a case of atypical thymic carcinoid that responded to neoadjuvant therapy with octreotide and sunitinib, an oral multikinase inhibitor. After 3 weeks of treatment, tumor size significantly decreased to allow for a safe surgical resection with clear margins. We believe that further study of sunitinib and octreotide with the neoadjuvant intent of preparing tumors for resection is warranted as a strategy to improve curative management of neuroendocrine tumors.
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Authors
Anu Dham, Alexander M. Truskinovsky, Arkadiusz Z. Dudek,