Oral squamous cell carcinoma with discoid lupus erythematosus

SummaryThis paper reports an interesting development in a 64 year old female originally referred for evaluation of oral lichenoid lesions. The patient had a previous diagnosis of discoid lupus erythematosus of the skin. The presenting oral clinical appearance varied between lichenoid areas and ectopic erythema migrans. At initial presentation the patient had an exophytic lesion on the vermilion of the lower lip and biopsy confirmed the clinical diagnosis of oral squamous cell carcinoma. She subsequently developed multiple lesions involving isolated oral sites as well as the lip.