Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3997439 | Seminars in Breast Disease | 2008 | 6 Pages |
Abstract
In vivo proton magnetic resonance spectroscopy (1H MRS) is rapidly becoming useful as a clinical tool for diagnosing and characterizing breast cancers. Alterations of the levels of choline-containing metabolites are associated with malignancy. High-field MR scanners at 1.5 T, 3 T, 4 T, and 7 T have been used to evaluate the role of 1H MRS measurements of total choline-containing compounds in patients with breast cancer. This article will review clinical use of MRI/MRS in vivo. Newer developments in high field MR scanning and quantitative MRS may help breast imagers improve sensitivity and specificity in diagnosing and treating breast cancer.
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Authors
Michael T. MD, Lenore I. MD, Michael PhD, Tim MD, Patrick J. PhD,