Targeted p21WAF1/CIP1 activation by miR-1236 inhibits cell proliferation and correlates with favorable survival in renal cell carcinoma

Our findings provide insight into the specific RNAa of miR-1236-targeted p21 promoter activation in suppressing RCC cell proliferation. Considering the poor prognostic outcomes associated with reduced miR-1236 and p21 expression, our data imply that these factors likely play important antitumor effects in RCC progression.