| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4000569 | Urologic Oncology: Seminars and Original Investigations | 2009 | 9 Pages |
Abstract
The present study describes an efficient RNAi system for gene silencing that is specific to prostate cancer cells using the PSMA promoter/enhancer. Suppression of STAT3 by using this system decreased proliferation and induced apoptosis of PC-3 and LNCaP cells. This system may be useful for RNAi therapy for prostate cancer.
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Authors
Weiming Ph.D., Yong M.D., Deling Ph.D., Ranlu Ph.D., Zijian M.S., Chengjun M.S., Zhihong M.D., Youcheng M.S.,