| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4000855 | Urologic Oncology: Seminars and Original Investigations | 2010 | 7 Pages |
Abstract
HDAC inhibitors can block bladder cancer cell cycle in vitro and induce apoptosis. The molecular mechanism may be associated with increased level of histone acetylation, down-regulation of p21WAF1/CIP1 expression, up-regulation of cyclin A expression, and dynamic change of bcl-2 and bax expression.
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Authors
Wei Ph.D., Yin-dong Ph.D., Mei-sheng Ph.D., Li-li Ph.D., Zhen-hao Ph.D., Li-ming Ph.D.,