Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4001221 | Urologic Oncology: Seminars and Original Investigations | 2008 | 6 Pages |
Abstract
Targeting PLCγ-1 by way of a hammerhead ribozyme to PLCγ-1 is an effective method in reducing invasive phenotype of prostate cancer. PLCγ-1 is a signalling intermediate that has prime influence on HGF induced cellular invasion and migration without affecting the growth of the cells.
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Authors
Gaynor Ph.D., Tracey A. Ph.D., Lin M.D., Jonathon M. M.D., Malcolm D. M.D., Wen G. M.D.,