Effect of Pupil Size on Corneal Aberrations Before and After Standard Laser In Situ Keratomileusis, Custom Laser In Situ Keratomileusis, and Corneal Refractive Therapy

The 3 techniques increase the wavefront aberrations of the cornea and change the relative contribution of coma-like and spherical-like aberrations. For a large aperture (> 5 mm), corneal refractive therapy induces more spherical-like aberrations than standard and custom LASIK. However, no clinically or statistically significant differences existed for narrower apertures. Standard and custom LASIK did not display statistically significant differences regarding higher-order aberrations.