Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4003777 | American Journal of Ophthalmology | 2010 | 11 Pages |
Abstract
Results of both TEM and immunohistochemistry indicate activation of unfolded protein response in Fuchs dystrophy. Unfolded protein response activation leads to endothelial cell apoptosis in Fuchs dystrophy and may play a central pathogenic role in this disease.
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Authors
Christoph Engler, Clare Kelliher, Arielle R. Spitze, Caroline L. Speck, Charles G. Eberhart, Albert S. Jun,