The In vitro Impact of Moxifloxacin and Gatifloxacin Concentration (0.5% vs 0.3%) and the Addition of Benzalkonium Chloride on Antibacterial Efficacy

As a preservative, MOX and GAT have equivalent antibacterial activity with similar killing rates. BAK appears to independently complement GAT for eliminating SA and CNS, but has no effect on PA. The in vitro predictive clinical effect due to varied antibiotic concentration and the addition of BAK requires confirmatory clinical studies for validation.